Some people seem to suffer more with bloating and gas when first beginning vitamin c therapy. Flushing and long term use seem to arrest this effect. Unless illness occurs then it reapers only to resolve once again. Researching this occurrence I found some profound information. It appears that this gas and bloat is a strong indication of inflammation.
“Isolation of bacteria capable of decomposing ascorbic acid from intestinal contents of adults, infants and certain animals, as well as from gastric washings of achlorhydrics was described in a previous study (Kendall and Chinn '38 a). It was shown that preliminary enrichment of source material in media containing ascorbic acid is a prerequisite for success (Kendall and Chinn '38 b). Furthermore, it was pointed out that ascorbic acid decomposing organisms thus isolated are specialized " strains" of bacteria, belonging for the most part to the strongly fermenting Mucosus capsulatus and Micrococcus ovalis groups rather than to definitive " species" of bacteria. This occurrence of bacteria among the multitude of intestinal microbes capable of utilizing ascorbic acid for energy requirements in absence of the ordinary carbohydrates, focuses attention upon several unexplored problems relating to their occurrence in the alimentary tract : their origin, numbers, acclimatization, and possibility of overgrowth in the intestinal environment”(Kendall A.Ph. D., et al.,1941).
“The ascorbic a cid fermenting bacteria were for the most part members of the Mucosus capsulatus and Micrococcus ovalis groups. However, a majority of the bacteria belonging to these groups were unable to ferment as corbic acid. This confirms the previously reported suggestion that the ability of bacteria to utilize ascorbic acid is a " strain" characteristic rather than a "species" characteristic”(Kendall A.Ph. D., et al.,1941).
So lets learn a little about mucosus capsulatus from HILDA R. HAY, M.B., CH.B., D.P.H.,:
“This was in marked contrast to the ease with which B. mucosus capsulatus was often isolated in cases of enteritis(inflammation). An attempt was made to discover the natural habitat of B. mucosus capsulatus in the gut by taking 4 samples of normal stools and examining a loopful of the mucus layer covering them, then after searing across the stool, examining a loopful of the solid matter. In 3 of the samples the surface mucus yielded plentiful colonies of B. mucosus capsulatus and B. coli, whereas the solid matter yielded B. coli almost entirely, but in much scantier growth. This would suggest that B. mucosus capsulatus is associated in the large intestine with the mucussecreting cells(Hay H., 1931).”
“The increased occurrence of B. mucosus capsulatus in inflammatory conditions of the gut appears to be due to an actual overgrowth(Hay H., 1931).”
Lets also look at micrococcus ovalis also known as enterococcus:
Interesting enough I also found that enterococcus is also associated with enteritis and diarrhea(Cheon, DooSung., Chae, Chanhee , 1996).
It is common for people to experience severe bloating and gas when they begin vitamin c therapy. We now know that this gas may be caused by the fermentation by Mucosus capsulatus and Micrococcus ovalis bacteria, Because these two species are strongly associated with inflammation, it apears that this fermentation is an indication that someones gut is suffering from enteritis.
The bloating and gas tends to disappear with vitamin c flushing and long term use. Perhaps this is due to excreting this specific bacteria and the anti inflammatory effects of vitamin c on the gut.
Kendall A.Ph. D., et al.,(1941). Observation on the Occurrence of Ascorbic Acid Fermenting Bacteria in the Stomachs of the Cow Studies in Bacterial Metabolism CXVII. l From the Departments of Research Bacteriology and Physiological Chemistry, Northwestern University Medical School, Chicago, Il: Pubmed.
Hay H., (1931). A STUDY OF THE BACILLUS MUCOSUS CAPSULATUS GROUP.Muirhead Research Scholar in Bacteriology, Royal Infirmary, Glasgow: Pubmed.
Cheon, DooSung., Chae, Chanhee (1996) Outbreak of diarrhea associated with Enterococcus durans in piglets. Journal Vet Diagnostic Investigation.
Vitamin C as ascorbic acid 16 oz. - Crystallized
One pound of high quality & GMO free ascorbic acid picked for it's purity.
*Immune System Support
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Larger orders will take a longer shipping/processing time.
GMO Free Sodium Ascorbate 16 oz.
One pound of high quality & GMO free sodium ascorbate.
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Larger orders will take a longer shipping/processing time.
The b vitamins are usually regarded together, after all they work synergistic-ally in the body. But, what if one of the b vitamins, alone, held astonishing healing abilities? It turns out that in 1952, Abraham Hoffer, PHD, MD, proved through a double blind placebo controlled study that vitamin b3 has the ability to cure schizophrenia(Hoffer A., Walker M., 1978). This knowledge is not mainstream and anti-psychotics with severe side effects continue to be used as the first line therapy. My research has uncovered a broad range of healing benefits by this vitamin. The mind, heart, brain, and skin all can be benefited by therapeutic doses of this nutrient. Vitamin b3 as an individual nutrient has an astonishing record of profound benefits to the human body.
There are many different forms of this vitamin: niacinamide, niacin, and inositol hexaniacinate. Niacin causes a flush of the skin in high doses while the other two forms do not. The type of vitamin b3 that a person chooses to supplement is based on personal preference. Some actually enjoy the flush that niacin causes. The common symptoms that are associated with a vitamin b3 deficiency are: fatigue, depression, digestive issues, diarrhea, low blood sugar, and insomnia. This vitamin is necessary to alleviate these deficiency symptoms but it also can be used therapeutically. To therapeutically use vitamin b3 involves doses much higher than the recommended dietary allowance. Allan Cott successfully used up to 3 grams of vitamin b3 in children with learning disabilities and Abraham Hoffer used much higher doses in his schizophrenic patients(Williams R Ph.d., et al., 1977). The need for this specific nutrient varies greatly from person to person. Some people may suffer from just a deficiency while others suffer from what Abraham Hoffer called a dependency. Schizophrenia is strongly associated with this dependency and that is why Hoffer had such great success with his 1952 study.
There is a large list of psychological disorders and every 1 in 4-5 American children are suffering according to the National Institute of Mental Health(Merikangas K., et al., 2010). This statistic is extremely disheartening and so is the fact that these children are being prescribed pharmaceutical drugs to fix their imbalance rather than uncover the root cause. An 8 year old girl suffering from severe tic’s and anxiety was given 500mg of niacinamide and found absolute resolution in less than a week(Gironda K., 2016). In an anonymous interview a mother disclosed to me that she began using vitamin b3 therapy on her child. She said, “there was eye blinking & rolling along with facial tics that diminished tremendously. I may even go as far as to say temperament is better than before & not as hyperactive(Anonymous, 2017). Learning and behavioral disorders in children are so widespread and can have a dramatic effect on families. Sometimes the greatest research comes from those that have lived and breathed mental disorder and resolved it themselves.
I grew up with an alcoholic father so I consider it a very troublesome mental disorder that effects everyone that person comes in contact with. A clinical trial was done on alcoholic’s anonymous members and twenty out of thirty subjects were alleviated of anxiety, fatigue, and tension in two months of taking vitamin b3(Wilson B., 1967). It turns out there are many physicians that use this amazing vitamin therapeutically. Dr. Russell Smith in Detroit is just one of them that has had great success with his alcoholic patients(Smith RF., 1974). It is baffling that one vitamin has the ability to positively impact those suffering from alcoholism.
Mental disorders are not the only health conditions that vitamin b3 is beneficial for. A recent clinical trial done by Brigham and Women's Hospital and Harvard Medical School found “a protective role of niacinamide, a derivative of niacin, against skin cancer recurrence”(Park S., et al., 2017). It turns out that niacinamide is a common ingredient found in skin care. My research turned up phenomenal scientific literature on the use of vitamin b3 in dermatology. A few of the conditions that either improved or entirely resolved are: actinic keratosis, bullous pemphigoid, dermatosis, acne, dermatitis, and psoriasis(Forbat e., et al., 2017). I stumbled upon another fascinating study from The Journal for British Society for Allergy and Clinical Immunology . They wrote that their study showed a link between lower levels of nicotinamide levels and related tryptophan metabolites in the pregnant mother and an increased risk of atopic eczema in their child(El-heiss s., et al., 2016). So not only can this vitamin be used therapeutically for skin conditions but there is a strong possibility that it can also be preventative of skin disorders through maternal supplementation.
It seems impossible that there are any more amazing therapeutic benefits of this vitamin. But, it turns out the supplementation of niacin is recommended by doctors for high cholesterol. Heart disease is the leading cause of death in the United States of all ethnicities according to the CDC(Mozaffarian D., et al., 2015). Statins are the drug of choice for lowering cholesterol nut because heart disease is so widespread, prevention is more important. The Atherosclerosis Research Center detailed the effects of niacin on cholesterol really well. They found that niacin reduces triglycerides and liporoteins by decreasing the mobilization of fatty acids from tissue stores and also raises HDL(Ganji S., et al., 2003). Therapeutic doses of niacin could make for an excellent preventative measure against heart disease.
Just when it seems like I can’t uncover anymore amazing benefits of vitamin b3, I come across a study on it’s ability to fight antibiotic resistant staph infections by increasing leukocytes, the bacteria destroying white blood cells. The researchers at Cedars-Sinai Medical Center found that high doses of niacinamide increased 1,000 times the capacity of the immune cells to kill Staphylococcus aureus bacteria. Their study was done on laboratory animals as well as with human blood. Clinical doses were able to destroy the staph infection in a few hours(Weeks B. MD., 2012). I decided to put this to the test and after my daughter caught strep throat. We used 500 milligrams of niacinamde 3 times per day along with high doses of vitamin c for immune support. Within 4 days she was symptom free. I have no doubt that vitamin b3 is a powerful tool against bacterial infections.
Through my research I have discovered that vitamin b3 appears to have vast benefits. It seems to be associated with increasing the health of many organs and physiological actions in the body. Allan Cott described the importance of vitamin b3 for proper brain function by improving tissue respiration(Williams R Ph.d., et al., 1977). This may be the science behind it’s nootropic benefits. I believe that there are more benefits to be discovered over time. From the heart to the skin this vitamin undoubtedly provides astonishing healing benefits.
Hoffer A., Walker M., (1978). Orthomolecular Nutrition. New Canaan, CT: Keats Publishing \/\lliams R Ph.d., et al., (1977). A Physician’s Handbook on Orthomolecular Medicine. New Canaan, CT: Keats Publishing Inc.
Park S., et al., (2017). Niacin intake and risk of skin cancer in US women and men. Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA: Pubmed. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/28152570
Forbat e., et al., (2017). Use of nicotinamide in dermatology. King Edward VII Hospital, London, UK: Pubmed. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/28052374
Merikangas K., et al., (2010). Lifetime Prevalence of Mental Disorders in US Adolescents: Results from the National Comorbidity Study-Adolescent Supplement. National Institute of Mental Health. Bethesda, MD: Pubmed. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946114/
El-heiss s., et al., (2016). Higher maternal serum concentrations of nicotinamide and related metabolites in late pregnancy are associated with a lower risk of offspring atopic eczema at age 12 months. University of Southampton. Southamptom, UK: Pubmed. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045718/
Wilson B., (1967). The Vitamin B-3 Therapy: The First Communication to A.A.'s Physicians and A Second Communication to A.A.'s Physicians,
Smith RF., (1974). A five year field trial of massive nicotinic acid therapy of alcoholics in Michigan. Journal of Orthomolecular Psychiatry.
Gironda K., Case Study. Franklin, NC: Revitalize Wellness. Retrieved from http://www.boweltolerance.org/casestudy1.html
Anonymous (2017). Personal Interview.
Mozaffarian D., et al., (2017). Heart disease and stroke statistics—2015 update: a report from the American Heart Association. U.S. Department of Health and Human Services. Atlanta, GA. Retrieved from https://www.cdc.gov/heartdisease/facts.htm
Ganji S., et al., (2003). Niacin and cholesterol: role in cardiovascular disease (review). Department of Veterans Affairs Healthcare System, Long Beach, California: Pubmed. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/12873710
Williams R Ph.d., et al., (1977). Vitamin B3 (niacinamide) to the rescue. WeeksMD. Retrieved from http://weeksmd.com/2012/08/vit-b-3-to-the-rescue/
Breastmilk is a powerful liquid. It has shown to hold some powerful antiviral and antibacterial properties. I megadose vitamin c on a daily basis and always thought that this was supplying my breastmilk with megadoses, Unfortunately, through testing I now know that my baby needs to be supplemented vitamin c as well. This winter she developed two ear infections, strep, and the flu. The ear infections and strep I was not supplementing her with vitamin c and she was extremely sick. She developed an ear infection and when it ruptured she developed bells palsy. At that time I began supplementing her with vitamin c apart from my megadosing and breastfeeding. She began to heal extremely well and when she developed the flu it consisted of a stuffy nose and a slight fever overnight. It was not as bad with the supplementation of vitamin c.
I decided to do a little experiment to see what was up with my breastmilk. I used Quantofix vitamin c test strips. I tested out my glass of ascorbic acid first and as you can see the concentration of vitamin c appears very high. My daughters test strip from urine appeared exactly the same color after I supplemented her with 2 grams of vitamin c. I tested my milk foremilk and hindmilk together before supplementation of vitamin c. The test strip shows 100 mg/L of vitamin c. I then drank 8 grams of vitamin c. My bowel tolerance is 3 but I wanted to flush to really see how bowel tolerance and flushing impact my milk. As you can see throughout this time of bowel tolerance, flushing, and an hour after there was no change in the concentration of vitamin c in my breastmilk. Just after the 8 grams my milk appears to show a darker color but no significant change.
I have concluded that megadosing moms should also be supplementing their babies with vitamin c for optimal health. There is just too much toxicity in our world to not be supplementing vitamin c. This dosage chart needs to also apply to megadosing breastfeeders.
This fall has brought on some very dry weather. As forest fires rage here in the Great Smoky Mountains so do skin conditions. Oftentimes if skin issues are related to detoxification or allergens, vitamin c therapy alone will resolve it. But those that use high doses of vitamin c regularly and experience skin ailments are looking for a way to ease their discomfort.
Borage oil contains high concentrations of a fatty acid known as (GLA) gamma-linolenic acid. Some of us do not convert linoleic acid into GLA adequatey due to either nutritional deficiencies or genetic dependencies. There are only a few really great sources known for their GLA content: Borage oil, black currant, and evening primrose oil.
The Institute of Gerontology at the University of Erlangen-Nürnberg found that "the consumption of borage oil induced a statistically significant improvement of cutaneous barrier function in the elderly people, as reflected in a mean decrease of 10.8% in the transepidermal water loss. Thirty-four percent of the people noted itch before borage oil consumption and 0% afterwards"(Brosche T., 2000). Borage oil supplementation and topic use can improve the health of the skin for those that suffer from skin disorders.
Borage oil does not just promote healthy skin, it improves the health of the entire body. Here is a list of things that this supplement is beneficial for:
Borage oil lowers inflammation in the body making it an excellent supplement for prevention against inflammatory diseases. Gamma-linolenic acid converts to prostaglandins, protecting the body from inflammation and reducing pain. Tannins within borage oil protects the brain from oxidative stress and improves cognitive performance and memory.
Adding this powerful supplement into ones diet along with vitamin c to bowel tolerance is a great idea. Especially those that suffer from inflammatory, behavioral, and skin disorders. When shopping for borage oil it is always best to look for organic options.
Brosche T., (2000). Effect of borage oil consumption on fatty acid metabolism, transepidermal water loss and skin parameters in elderly people. University of Erlangen-Nürnberg.
Nürnberg, Germany: Pubmed.
I have been playing around with different recipes for a a year now and have finally found one my kids love! They ate so many of these last night that I had to hide them just so they wouldn't flush.
Here's what you need:
2 Cups of water or 2 cups of juice
2 Packs of powdered drink mix(2 teaspoons)
6 Tablespoons of gelatin
8 Teaspoons of ascorbic acid
2 Teaspoons of sodium bicarb
Pour a little of the water into a separate cup with 8 teaspoons of ascorbic acid and 2 teaspoons of sodium bicarb. Let that fizz.
Heat up the rest of the jwater and mix in 2 packets of a powder flavored beverage. The water does not need come to a boil. Add in 6 tablespoons of gelatin and mix until fully dissolved. Remove from heat and once cooled down enough, add the vitamin c. Mix until well blended. Pour into glass dish and stick in the fridge. Cut into 32 squares that are 1 gram of vitamin c each. Enjoy!
Mother's across the United States are enraged as Hyland's Teething Tablets are pulled from the shelves everywhere. Some mother's are even seeking the remaining boxes before they are untraceable. This recall does not come as a surprise considering the many accusations they have encountered in regards to the safety of their product. This homeopathic remedy for a fussy teething baby actually works due to it's active herbal ingredients. But, do the benefits outweigh the risks?
Let's look at the accusations in regards to the safety of these teething tablets. A video is circulating the internet of a small child whose nervous system is clearly not working normally, as she leans her head down involuntarily. There have not only been neurological symptoms such as seizures, but this homeopathic remedy has been linked to 10 deaths. In an attempt to defend Hyland's homeopathic remedy, mothers are claiming that some parents don't follow the directions or claiming that the FDA is just out to get this product because it works.
Unfortunately, the FDA's decision to recall this product comes justly. Atropa Belladonna also known as deadly nightshade is a solanaceae plant that is highly toxic due to it's active constituents: atropine, hyoscyamine, and scopolamine. According to David Hoffman a clinical phytotherapist, "a prominant feature of the tropane alkaloids is their ability to produce hallucinations and delirium" (Hoffman D., 2003). Atropine toxicity involves symptoms such as dry mouth, dizziness, and even a skin rash. Hyoscyamine toxicity may be apparent with symptoms such as dizziness, nausea, and blurred vision. The Alfred Hospital in Victoria, Australia found that "the range of toxicity with respect to oral scopolamine is variable and unpredictable" (Corallo C., 2009). Perhaps because the genetic makeup of each individual is different. One individual may experience a reaction to an active constituent within an herb, while another individual may not react till they reach a much higher dosage. Electron flow within the body strongly influences a persons adverse reaction. Those with high a antioxidant status will be able to tolerate much higher levels of toxins. A child with low antioxidant status will experience adverse reactions to pyrrolidine-piperidine alkaloids at lower doses. Vitamin c has the potential to negate adverse reactions to the alkaloids within the belladonna herb, but there is still no telling how much is enough. The safest option is to avoid them unless under the care of a certified herbalist.
So how does a parent go about easing the pain associated with teething? Tylenol is never a good option as it is toxic to the body. With high enough concentrations of vitamin c in the body a child will feel no teething pain. This can be achieved by supplementation of oral ascorbate. The difference between vitamin c and belladonna is vitamin c has no toxic dosage. If mother is breastfeeding she can take what is known as bowel tolerance doses to achieve high levels for her and her child. If mother is bottle feeding, 250mg can be added to each bottle, if necessary that dosage can go up as baby gets older. If loose stools occur it is good to lower the dose. If the tooth is just breaking through the skin sodium ascorbate can be mixed with a drop of water. After fizzing has stopped apply the paste directly to babies painful gums.
Many parents are disappointed to see Hyland's teething tablets go. But, there are other ways to manage your babies discomfort that are even more natural and safe than the tablets. Unfortunately, the safety of tropane alkaloids are unstable and parents are better off finding safer natural remedies.
Hoffmann D., (2003) Medical Herbalism: Tropane Alkaloid's. Healing Arts Press: Richmond, VT.
Corallo C., (2009). Anticholinergic syndrome following an unintentional overdose of scopolamine. Department of Pharmacy, The Alfred, Melbourne, Victoria, Australia: Pubmed.
Metabolic Syndrome X (MSX) is a constellation of 5 risk factors that greatly increase one's chances of developing
Type 2 diabetes, heart disease, and stroke. It is not a disease per se, but is rather an indication of a worsening
metabolic environment that paves the way for disease. It is highly important for the student of nutrition or dietetics to
understand this condition since 68,000,000 American's have this condition per the 2006 NHANES III study; roughly
32 % of the population. (2) Those at greatest risk are those over 55 who are sedentary and obese. Smokers and
heavy drinkers are also at greater risk. However, the NHANES study also noted that teens can have this syndrome so it
is certainly not limited to the elderly and middle ages. Also, perhaps more alarmingly, the study noted a 34% increase
in prevalence from 1990-2006 in women ages 20-39. It was much less common in this age group before 1990 and the
increase in prevalence tracks with the increase in obesity rates that the study also notes from that time period.
Defining Metabolic Syndrome X:
Many different groups have put forth varying definitions of what comprises MSX, such as the American Diabetes
Association, the American Heart Society and other such medical groups. I have chosen to use the definition offered
by the National Cholesterol Education Program (NCEP) Adult Treatment Panel III (ATP III), which states that MSX can
be diagnosed upon confirmation of 3 of the 5 symptoms: 1. Obesity as defined as a waist circumference over 40
inches for men and 35 inches for women, 2. Hypertension measuring greater than 135/80 mmHg, 3. Insulin
Resistance measured by a fasting glucose over 100 mg/dl, 4.Fasting triglycerides over 150 mg/dl, 5. Fasting HDL
Cholesterol less than 40 mg/dl for men and 50 mg/dl for women. Some definitions differ as to whether more
emphasis is placed on insulin resistance or obesity but all the definitions included these two factors. It is possible to
be obese and not have any other symptoms of MSX, so it is clear that obesity partnered with insulin resistance is
crucial to the diagnoses. And when one takes a look at the molecular mechanisms that underlie this condition one
can see why. Obesity and insulin resistance together lead to the other three risk factors which in turn worsen the
obesity and insulin resistance. It really becomes a vicious cycle where each risk factor feeds into the next. (1)
Molecular Mechanisms in Metabolic Syndrome.
Insulin resistance is a key component as mentioned above, without which we cannot diagnose MSX, which is
reasonable as the MSX is a strong predictor of developing type 2 diabetes, and is often referred to as
pre-diabetes. The main role of insulin in human metabolism is in the utilization of glucose, where it stimulates the
of glucose into the cells of skeletal muscles and adipose tissue by way of the GLUT 4 glucose transporter. In adipose
tissue insulin inhibits lypolysis and promotes the storage of glucose and thus clears it out of the blood which protects
the body from the negative effects of high blood sugar. Insulin, when bound to the insulin receptor and
phosphorylated by tyrosine kinase, activates two parallel metabolic pathways, the phosphoinositide 3-kinase
(PI3K-Akt) pathway, and the mitogen-activated protein (MAP) kinase pathway. The
PI3-AKt pathway is critical to much of the downstream activity of insulin and is involved in the other risk factors of
MSX as well. This pathway phophorylates endothelial nitric oxide synthase (eNOS), which is critical for endothelial cell
function, and this pathway also activates the GLUT4 transporter. The MAP kinase pathway is also critical for
endothelial function and when stimulated it releases endothelin 1 which leads to vasoconstriction and increase the
risk of atherosclerosis, when not properly balanced by nitric oxide. In insulin resistance the MAP Kinase pathway is not
inhibited, but the PI3-Akt pathway is, which puts them out of balance. Thus we can see that there will be less
eNOS activity and lower levels of nitric oxide to balance out endothelin-1, as well as inhibited GLUT4 activity
leading to a rise in blood sugar levels. The lower levels of nitric oxide also lead to reduced blood
flow which explains the issues that diabetics often develop with circulation to the lower extremities.(1)
Obesity stimulates the release of adipokines such as TNF-alpha and
IL-6 which are inflammatory agents and increase insulin resistance (IR) and oxidative stress. Obesity also
stimulates the renin-angiotension system which contributes to hypertension and IR. The inhibition of the
PI3-Akt pathway is also initiated by obesity, through the release of excess amounts of free fatty acids (FFA's) into
the blood stream. Finally, the benefical adipokine, adiponectin, is suppressed in obesity. Adiponectin serves to
couple insulin with energy production and its suppression leads to IR. (1)
Dyslipidemia in MSX is featured as high triglycerides (TG) , low HDL count, and increased numbers of VLDL. IR and
visceral obesity directly contribute to these risk factors. Insulin suppresses lipolysis as noted above. When IR is
present, lipolysis is increased, leading to excess FFA's which are the substrate for TG production in the liver.
Increased FFA also stabilizes apoB, which is the major component of VLDL cholesterol, increasing its production.
Insulin also is critical in degrading apoB via the
PI3-Akt pathway, but since this pathway is inhibited in IR, apoB and VLDL will rise. IR also suppresses the production
of lipoprotein lipase which mediates VLDL clearance which leads to high TG levels. HDL is reduced due to the high
VLDL levels. The TG in VLDL can be transferred to HDL cholesterol where the liver will prefer it as a good substrate
for hepatic lipase and clear HDL from the blood, leading to reduced levels, which in turn greatly increases the risk of
Endothelial dysfunction, with the combined downstream risks of atherosclerosis and hypertension are the final
mechanism to review. Normal endothelial function is critical to proper blood flow, resisting the developing of arterial
plaques, and proper blood pressure. Phosphorylation of the endothelial nitric oxide synthase (eNOS) enzyme is
critical to endothelial function and many of risk factors of MSX work together to suppress this enzyme and as a result
less nitric oxide is available to maintain endothelial health. Hyperlipidemia, diabetes and atherosclerosis all suppress
eNOS phosphorylation. As mentioned above it is stimulated by the
PI3-Akt pathway and when this pathway is inhibited by insulin resistance phosphorylation cannot occur, or occurs
at a reduced rate. Adiponectin, also increases eNOS phosphorylation, but this is also suppressed by IR. Also as
mentioned above the MAP Kinase pathway is not inhibited by IR and this being out of balance with the
PI3-Akt pathway creates endothelial dysfunction. Obesity contributes to endothelial dysfunction via the deleterious
effects of TNF-alpha, and IL6.
TNF-alpha stimulates lipolysis which increases FFA levels which as discussed above leads to dyslipidemia.
TNF-alpha also activates NADPH oxidase which creates excess superoxide. Leptin resistance, caused by visceral fat
also increases ROS production, leading to greater inflammation and worsening IR. As vasoconstriction occurs, the
blood flow to skeletal muscles is less efficient, which means the muscles can take up less glucose. In this way we can
see that endothelial dysfunction will worsen IR, which in return will further worsen endothelial dysfunction, creating a
ever worsening situation until full-blown diabetes develops.
Nutritional Factors of Metabolic Syndrome X
MSX is more a disorder of over consumption of the wrong things rather than a disease of pure nutritional deficiency
like scurvy or pellagra. There are however a few key nutrients that if deficient greatly increase one's chances of
developing MSX. The first culprit to look at is trans fatty acids (TFA's). These are saturated fatty acids that have been
hydrogenated to be in the trans configuration, meaning with the double bonds to be one side, and therefore to lack
the 'kink' that cis fatty acids have. This makes them lie closer together and to achieve solidity at room temperature as
well as to be able to withstand high cooking temperatures. They were introduced into the American diet through
products like Crisco in the mid 20th century and became ubiquitous in everything from cooking oil to snack cakes.
Research has proven conclusively their deleterious effects and they are not as prevalent on the market as they once
were (in the US and Europe), but one can still find them in many products sold in supermarket shelves . TFA's are
recommended to be no more than 1% of daily energy consumption to avoid health issues. They can occur naturally in
red meat from ruminants, but in small amounts, so it is not difficult to reach the less than 1% goal even if one ate red
meat every day. TFA's contribute directly to the molecular mechanism discussed above. High amounts of dietary
TFA's, meaning amounts over 2% of energy product directly lead to reduced HDL cholesterol, worsening apoB to
apoA1 ratio, and higher triglycerides, as well as decreased LDL particle size. This occurs as TFA's will directly increase
the production of TNF-alpha in obese and even non-obese subjects. They also directly increase
E-selection which leads to vasodialation, and increase visceral fat which contributes to IR. IL6 levels and C reactive
protein levels are also increased. Free Fatty acids will also be increased which will lead to greater triglycerides as
discussed above. (3)
Almost as harmful as TFA's is high fructose corn syrup. In reality, it is simply the high amounts of fructose in the diet
that are the problem, but HCFS is an egregious offender as it is an unnatural substance that delivers higher amounts
of fructose not found in nature. HFCS can contain as much as 90% fructose but most soft drinks use a 55% fructose
solution which represents 42% of caloric sweeteners added to foods and beverages. In 1978 the percentage of HFCS
in food was 16% versus the 42% levels of today. This is also the same time period when obesity and diabetes and
MSX levels were skyrocketing. Like TFA's, HFCS in these amounts directly contribute to the mechanisms of MSX. As
discussed above glucose enters the cell via the GLUT4 transporter. This is mediated by insulin, and the amount of
glucose that can be converted to triglycerides is further moderated by phosphofrucktokinase, and signals satiety to
the brain. Fructose on the other hand enters the cell via the GLUT5 transporter which is not mediated by insulin. It
does not signal satiety to the brain, and this makes it easy to overconsume as millions of teens demonstrate everyday
by consuming a 64 oz Mountain Dew from convenience stores. Once in the cell, aldolase can easily cleave the
molecule to form trioses that participate in triglyceride formation much more efficiently than glucose does, as it is not
regulated by phospofructokinase. Thus we can see that high consumption of HFCS will lead to hypertriglyceremia
which as we have seen earlier leads to insulin resistance. HFCS also stimulates NADPH oxidase which increases ROS
which reduce beta activity in the pancreas and leads to IR. It is also important to note that even in individual who do
not have obesity, or diabetes or hyperlipidemia, HFCS is associated with
non-alcoholic fatty liver disease. This is due to HFCS causing dysregulation of the mitochondria in hepatocytes. (4) This
evidence makes it clear that HFCS is a standalone risk factor for MSX, and I think a more important one than TFA's.
Although TFA's are worse, they are not as ubiquitous in American society as HFCS which is consumed every day by
millions of Americans. (4)
Along with these two dietary factors, there are a few specific nutrient deficiencies that increase the risk of
developing MSX. Lack of vitamin K is one such deficiency. Per the source's review of the NHANES study there is an
inverse relationship with vitamin K levels and lipid dysregulation as well as hypertension, with a p value of .05. HDL
and CRP levels also showed improvement along with hyperglycemia. The researchers don't exactly know the
underlying mechanism of why this is the case. The deficiency of vitamin K is widespread due to the lack of leafy
greens in the standard American diet. (9) The lack of greens also contributes to magnesium deficiency is also
implicated in the development of MSX. The typical American diet is often high in calcium, due to supplementation
or over consumption of dairy foods like milk or cheese. Yet it is much less replete in magnesium unless one eats a
great deal of high magnesium foods like kale or spinach or pumpkins seeds, or supplements. The dietary imbalance
of Mg to Ca leads to an intracellular imbalance, via activation of the
n-methyl aspartate receptor, and this leads to IR due to a worsening effect on glucose metabolism. The key is the ratio.
It was found that diets that were poor in both Mg and Ca had the highest risk, diets with normal CA and low Mg were
at some risk, and diets replete in both Mg and Ca were in the least risk. Supplementing with magnesium makes a
great deal of sense for anyone at risk of MSX. This is a nutrient that will directly increases the risk of MSX in its
absence and reduces the risk when supplemented or consumed in the diet and it should be considered by anyone
who has or is developing MSX. (5) It has also been noted that those with MSX are deficient in vitamins C and E as well
as other antioxidants. Source 10 finds that ''high levels of oxidative stress deplete endogenous and exogenous pools
of antioxidants'' and as we discussed above, there is much oxidative stress associated with metabolic syndrome. (10)
Medical Treatment of MSX.
Medical treatment is focused on managing the symptoms associated with MSX. There is no one drug that will reduce
all the risk factors, unless that were a drug that could help someone lose weight. Insulin resistance can be treated
with oral drugs such as metformin that improve glucose metabolism. If oral drugs aren't successful, then daily insulin
can be injected to maintain blood sugar levels. Hypertension can be treated with calcium channel blocker, ACE
inhibitors, diuretics, or beta blockers. Hyperlipidemia can be treated with statin drugs or drugs that target triglycerides.
There is an overlap between the therapies that doctors would recommend and what a nutritionist might recommend.
Both agree that the first and best therapy is weight loss and improving the diet. Losing just 10% of body weight will
lead to a reduction in all the 5 symptoms. Exercise has been noted to improve HDL cholesterol levels and to reduce
hypertension. Certainly doctors and nutritionist alike will encourage a more nutritious diet that feature reduced HFCS
trans-fats, and less saturated fats. Cessation of smoking is very important for reducing hypertension and lowering
the risks of heart disease. Cessation or reduction of alcohol consumption is also critical to prevent the worsening of
fatty liver which so often accompanies metabolic syndrome. There is also a direct link to alcohol consumption and
insulin resistance and many doctors will stress these common sense lifestyle changes as part of their medical advice.
Dietary Strategies for Metabolic syndrome.
Beyond the basic advice of exercising more and trying to lose weight, there are specific dietary strategies that can be
implemented that will directly improve the markers of metabolic syndrome. The Mediterranean diet is one such
effective strategy. Source 6 concludes that This is a diet that focuses on low saturated fats, low simple carbs and
replacing those calories with calories from mono unsaturated fats such as found in olive oil and nuts, as well as with
PUFA's such as in seeds, nuts and fish. It has been found that " the replacement of carbohydrate and saturated fat
with MUFAs leads to reductions in glucose and blood pressure and to an increase in HDL in patients with diabetes" so
this dietary factor is directly helpful. N-3 and
N-6 PUFA's also have an inverse relationship with heart disease. I was suprised that omega 6 intake was shown to
improve metabolic syndrome directly, as Omega 6 oils have a poor reputation in the press as being inflammatory.
(12) One study found that 30 grams of walnuts per day, which are an excellent source of
alpha-linoleic acid, improved the HDL to LDL ratio, reduced the total cholesterol, and also improved endothelial function.
N-3 PUFA's from fish oil that are high in DHA and EPA are of particular importance. Diets high in fiber have also been
shown to improve insulin resistance and FFA acid levels. Ideally the diet will include indigestible as well as
fermentable fiber and low glycemic starches. The Mediterranean diet is one example where little red meat is eaten,
and instead there is a great deal of fish, nuts, seeds and whole grains. It has been studied and found to a be a
cardioprotective diet as it naturally adheres to what has been discussed above. (6)
When I choose this topic I was really curious as to whether low carb diets such as the Atkins Diet or South Beach diet
would have a positive effect on metabolic syndrome patients. Source 7 is study that I found fascinating that directly
compares the results of a low carb diet vs. a high carb low fat diet such as the USDA Myplate. The study was 12 weeks
in duration, and the focus was directly on the metabolic impact of the diet as measured by bloodwork, on the
markers of metabolic syndrome. The high fat diet used a ratio of carbs/fat/protein of 12:59:28 and the high carb diet
was 56:24:20, but both diets maintained the same caloric intake of 1800 calories. The first observation was that the
high fat dieters lost more weight during the 12 weeks with 19/20 subjects losing greater than 5% of their body weight,
with 9 of them losing 10%. On the high carb diet only 12 subjects lost 5% and none of them lost 10%. Fasting
glucose was improved by 12% on the high fat subjects, and no improvement on the low fat cohort. Fasting insulin was
reduced by 47% vs 17%. These two findings are hugely significant as if the insulin response can be improved this
significantly than the metabolic syndrome is being reversed. Triglycerides improve by 57% on the low carb vs 24% on
the low fat diet. HDL cholesterol is improved by 13% vs 1% and the LDL particle size was also improved on the low
carb diet, no change on the low fat diet. This finding shows a reduction in the risk of athersclerosis. Further reducing
the heart disease risk was the improvement in APOb|APO a1ratio, which has an impact on cholesterol particle size.
Unique to this study was the measuring of serum retinol binding protein 4. This protein has a direct impact on insulin
resistance and it was reduced on the low carb diet and not at all on the low fat diet. This study makes it clear that over
a 12 week period at least there are many metabolic benefits to a low carb high fat diet vs a more traditional diet
approach. The fact that there is so much measurable improvement in the risk factors of MSX suggest this may be an
good alternate approach and I see it as an alternate strategy for a diet like the Mediterranean diet. (7)
Along with diet there are several supplemental strategies that research has supported as being useful either to all the
symptoms of MSX or to one or more of the risk factors. Correcting magnesium and calcium deficiency is of critical
importance as discussed above. Ensuring the RDI of both delivers the best results as noted in source 5:
" Randomized controlled trials have shown that oral Mg supplementation of 250 and 365 mg/d for 3 and 6 months,
respectively, reduced insulin resistance, and Mg supplementation of 382 mg/d for 4 months improved blood
pressure, fasting plasma glucose and TAG" (5) Supplementing with Vitamin K as mentioned above, largely to correct
the deficiency can reduce the risk of MSX. If one cannot afford adequate fish in their diet, or is perhaps concerned
about the mercury content of fish, then supplementing with fish oil is beneficial as source 6 finds that "1 gram of fish
oil taken for a 12 month period was found to reduce TG levels, liver enzymes, liver steatosis, and TNF-alpha."
(6)(11) If one adds Niacin to their N-3 fish oil, there is a synergistic effect on the
APOb|APO-a1 ratio and the rest of the apoliproteins, and it was found to be more beneficial than taking fish oil
by itself. (8) Source 10 looked at antioxidants and recommends that patients with diabetes or
metabolic syndrome increase their intake of C and E in particular. The researchers found that ." The effects of
vitamins C and E have received a great deal of interest. Through effects on oxidation of LDL cholesterol concentration,
leukocyte adhesion, and endothelial function, vitamins C and E may slow atherosclerosis. For example, vitamin
C and E intakes were positively associated with paraoxonase activity." Paraoxonase enzymes have been proven to
be preventative against atherosclerosis and
are anti-oxidative. (10) Earlier we discussed how nitric oxide product is a key risk factor for heart disease and
hypertension and source 13 finds that "
α-Tocopherol enhances NO production, and its supplementation in hypercholesterolemic men and smokers
preserves endothelium-dependent vasorelaxation." and supplementation with a full spectrum
E vitamin is recommend. (13) Source 14 is a
meta anlysis of 13 studies on the effects of Vitamin C on LDL cholesterol, HDL and triglycerides. 500 mg of
supplemental vitamin C per day was found to reduce TG by 20 mg/dl and LDL cholesterol by 7 mg/dl. There was
not significant increase in HDl. (14)
Metabolic syndrome is largely disorder of obesity and insulin resistance especially when combined with
hypertension and dyslipidemia. The consumption of harmful substances increases its risk greatly. It can be reversed
with careful dietary choices. Low carbohydrate diets are of particular note in treating metabolic syndrome.
Supplementation of certain nutrients can reduce the risk of MSX, or control some of the symptoms.
1. Paul L. Huang, A comprehensive definition for metabolic syndrome, Disease Models and Mechanisms. 2009
May-Jun; 2(5-6): 231–237.
2. Arupendra Mozumdar, PHD and Gary Liguori, PHD, Persistent Increase of Prevalence of Metabolic Syndrome
Among U.S. Adults: NHANES III to NHANES 1999–2006 , Diabetes Care 2011 Jan; 34(1): 216-21
3. Renata Micha & Dariush Mozaffarian Trans fatty acids: effects on metabolic syndrome, heart disease and diabetes,
Nature Reviews Endocrinology 5, 335-344 (June 2009
4. Ferder, L., Ferder, M.D. & Inserra, F., The Role of High-Fructose Corn Syrup in Metabolic Syndrome and
Hypertension Curr Hypertens Rep (2010) 12: 105
5. Moore-Schiltz, L., Albert, J.M., Singer, M.E., Swain, J. and Nock, N.L. (2015) ‘Dietary intake of calcium and
magnesium and the metabolic syndrome in the National Health and Nutrition Examination
(NHANES) 2001–2010 data’, British Journal of Nutrition, 114(6), pp. 924–935.
6. Angela M Zivkovic, J Bruce German, and Arun J Sanyal. Comparative review of diets for the metabolic
syndrome: implications for nonalcoholic fatty liver disease The American Journal of Clinical Nutrition , August 2007
vol. 86 no. 2 285-300
7. Jeff S. Volek,, Stephen D. Phinney, Cassandra E. Forssythe, et al. Carbohydrate Restriction has a More
Favorable Impact on the Metabolic Syndrome than a Low Fat Diet. Lipids April 2009, Volume 44, Issue 4, pp 297–309
8. Savinova OV, Fillaus K, Harris WS, Shearer G, Effects of niacin and
omega-3 fatty acids on the apolipoproteins in overweight patients with elevated triglycerides and reduced HDL cholesterol.
9. Pan Y1, Jackson RT. Dietary phylloquinone intakes and metabolic syndrome in US young adults. J Am Coll
Nutr. 2009 Aug;28(4):369-79.
10. Earl S. Ford, Ali H. Mokdad, Wayne H. Giles and David W. Brown The Metabolic
Syndrome and Antioxidant Concentrations Diabetes Sep 2003, 52 (9) 2346-2352
11. Yong-Seok Kim,1,2 Pengcheng Xun,1 and Ka He1 Fish Consumption,
Long-Chain Omega 3 Polyunsaturated Fatty Acid Intake and Risk of Metabolic Syndrome: A
Meta-Analysis Nutrients. 2015 Apr; 7(4): 2085–2100. Published online 2015 Mar 24
12. Mauno Vanhala*, Juha Saltevo, Pasi Soininen, Hannu Kautiainen, Antti J. Kangas,Mika
Ala-Korpela and Pekka Mäntyselkä Serum
Omega-6 Polyunsaturated Fatty Acids and the Metabolic Syndrome: A Longitudinal
Population-based Cohort Study Am. J. Epidemiol. (2012) 176 (3):253-260.
13. Pankaj Mathur MD,Zufeng Ding PhD,Tom Saldeen MD, PhD,Jawahar L. Mehta MD, PhD Tocopherols in the
Prevention and Treatment of Atherosclerosis and Related Cardiovascular Disease, Clinical Cardiology, 14 August
201514. McRae MP. Vitamin C supplementation lowers serum
low-density lipoprotein cholesterol and triglycerides: a
meta-analysis of 13 randomized controlled trials. J Chiropr Med. 2008 Jun;7(2):48-58.
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Infertility is estimated to affect 1 in 6 couples. The desire to bring new life into the world is a great one and the
inability to do so can be discouraging. Couples seek out cause and resolution with infertility. There are many
causes of infertility such as estrogen dominance, deficiencies, and toxicity. The human body is designed to
reproduce and create life. The most important thing a person experiencing infertility must do is evaluate their
lifestyle. A delicate life cannot grow healthily within a
sub-optimal environment, which means a mother must nourish and cleanse her body before she carries a child.
This will give herself and her child the greatest chance at a healthy pregnancy, birth, and life.
Vitamin c is the most vital nutrient for a healthy pregnancy. The corpus luteum is a cyst that develops after an
ovum has been released from an ovary. This cyst secretes progesterone, maintaining the endometrium so that it
does not shed if the ovum and sperm fuse. The corpus luteum contains twice as much vitamin c in a pregnant
female than a non pregnant one. Women that rely on diet alone to get their vitamin c will have inadequate levels
to maintain a healthy luteal cyst. This inadequacy will likely prevent a pregnancy from progressing. Cord blood and
amniotic fluid contain twice as much vitamin c than that of the mothers blood levels. Interesting how the mothers
body seems to favor the baby with vitamin c. Perhaps, the baby is favored because vitamin c neutralizes toxins and
has a protective effect on the baby.
If the father-to-be suffers from infertility it is most likely a direct result of inadequate vitamin c levels.
Scientific literature shows that unhealthy sperm is associated with low levels of this
vital nutrient. The University of Rochester Medical Center in New York found that “men with insufficient seminal
ascorbic acid frequently have sperm DNA damage” (Song G., 2006). Considering a large number of miscarriages
are genetically caused, evaluating the nutritional status of the man is very important. Another study was
conducted by Dubai Specialized Medical Center and Research Lab and they found that “vitamin C
supplementation in infertile men might improve sperm count, sperm motility, and sperm morphology and might
have a place as an additional supplement to improve the semen quality towards conception” (Akmal M., 2006).
Strong evidence points towards the fact that infertility is associated with low vitamin c levels in the body for men
and women. This may be due to the fact that vitamin c is used up rapidly by neutralizing oxidative stress. By
supplementing this vital nutrient consistently in high doses throughout the day one can be certain their body is
getting what is required for a healthy pregnancy.
Israel S. (2008) Progesterone-like Effect of Ascorbic Acid on the Endometrium. Department of Gynecology and the Laboratories, Mount Sinai Hospital. Philadelphia, PA. Retrieved from http://press.endocrine.org/doi/abs/10.1210/endo-29-2-210
Heinz-Erian P, Achmüller M, Berger H, Brabéc W, Nirk S, Rufer R., (1987). Vitamin C concentrations in maternal plasma, amniotic fluid, umbilical cord blood, the plasma of newborn infants, colostrum and transitory and mature breast milk. Padiatr Padol. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/3614950
Song G., (2006). Relationship between seminal ascorbic acid and sperm DNA integrity in infertile men.
Department of Obstetrics and Gynecology, University of Rochester Medical Center, Rochester, NY: Pubmed.
Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/17121654
Akmal M., (2006). Improvement in human semen quality after oral supplementation of vitamin C. Dubai
Specialized Medical Center & Research Labs, Dubai: Pubmed. Retrieved from
I used to think of candida as a predator, stealing all the good in my body for itself. When I first started reading about candida overgrowth and how to overcome it, I was overwhelmed by the tortuous diet that would be required. The point of the candida diet is to starve it to death. So I began by consuming only vegetables, meat, fat, almonds, and brown rice. Weight dropped off of my body like I was shedding my winter coat. I don’t recall ever feeling better in the year I was on the candida diet, in fact I felt worse. With many hospital visits and late night google searches something was still missing. On this diet I may have been starving the candida to death but the problem was, I was also starving myself.
My body was covered in tinea versicolor. They say your skin is a mirror into your body which meant I was full of fungus. Candida pokes holes in the gut and food enters the blood stream creating igg mediated reactions also known as sensitivities. These delayed hypersensitivity reactions are so extreme that they can include symptoms such as a rash, backache, cough, hyperactivity, tic’s, numbness, and blurred vision. This list barely touches symptoms that are possibly caused by igg mediated reactions.
Candida, the big bad wolf is actually not so bad, in fact it is meant to live peacefully within our bodies Candida absorbs heavy metals to keep them from entering the blood stream, protecting us as a result. We all know how dangerous heavy metals are, especially mercury. If you have amalgams you probably have candida. Candida is never the cause of illness it is always the side effect. If you have candida then it’s pertinent you search for the true source of your illness.
Dental toxicity, malnutrition, and environmental toxin exposure are just some of the possible causes of illness and candida overgrowth. Whatever it may be vitamin C is the answer. By flushing the digestive tract you will flood your gut with all those cell saving electrons and push pathogens out into the porcelain throne where they cannot harm you anymore.Your gut bacteria will celebrate and start building up their habitat. Keep feeding your healthy bacteria and flushing regularly to push those pathogens out before they can spread.
Candida is not to be destroyed. We want to provide an environment where the candida does not need to spread and cause damage. We want a healthy body where we can live in harmony with it.
It took me three months to fully recover from my delayed hypersensitivity reactions. I watched the candida overgrowth be excreted and balanced. I still, after several years look and feel better with the help of vitamin c. My tinea versicolor has been gone for years. I am no longer on any sort of diet and enjoy every healthy day I have. Stop worrying about crazy diets and pharmaceutical antifungals. Ascorbic acid, vitamin c has the potential to detox and help you heal, you just have to provide your body with enough of it.
Forty-four years ago the autism prevalence rate was less than 1 per 10,000 and now
the rate has grown to 1 in 68 children, according to the Center for Disease Control
(Christensen D., 2016). At this pace the autism rates will be 1 in 2 by 2050. The vaccine
debate is not a new trend brought on by rebellious googling moms, but an old revolution
commenced by doctors with great reason. In 1876 Dr. James Wilkinson said:
“Compulsory vaccination is an instance of a law which inflicts actual disease and
possible death on the human body and propagates disseminates deadly infections widely
upon animals and mankind. This is surely a glaring instance of a law which is not based
on wisdom or sanity and is a menace to the health and security of humanity and the state.
This amazing act is the homicidal insanity of a whole profession. This is blood
assassination” (Higging C., 1920). It is extremely important to uncover just what causes
autism before this epidemic is insurmountable. According to scientific literature, autism
appears to be undoubtedly associated with the administration of vaccines.
Autism is a term used to describe a group of complex brain development disorders.
Some of the worse symptoms associated with autism are self-harm, repetitive movements,
compulsive behavior, learning disabilities, speech delay, anxiety, and even tic’s.
Vaccines were designed to stimulate the production of antibodies, providing
immunity against diseases. Approximately 49 doses of vaccines are recommended before
a child turns 6. But what exactly is in a vaccine? The Center for Disease Control provides
a list of ingredients on their website: “FD&C Yellow #6 aluminum lake dye, human
serum albumin, fetal bovine serum, human-diploid fibroblast cell cultures (WI-38),
Dulbecco’s Modified Eagle’s Medium, monosodium glutamate” (Grabenstein JD., 2013).
The University of British Columbia found that “in young children, a highly significant
correlation exists between the number of pediatric aluminum-adjuvanted vaccines
administered and the rate of autism spectrum disorders” (Sgaw CA., 2013). Seizures are
one of the symptoms of aluminum toxicity and they are also one of the many reactions
children experience after being vaccinated. Cells harvested from calf fetuses, components
of another human’s blood, lung tissue from aborted fetuses, and MSG are alarming
ingredients being injected into newborns through vaccines. The most troubling of
ingredients are the heavy metals: mercury and aluminum. The School of Medicine at
Fu-Jen Catholic University concluded from a study that excess aluminum accumulates in
certain areas of the brain inducing oxidative damage (Yuan C. 2012). It is said that
thimerosal has been removed from vaccines with exception of the flu shot that is still
recommended for children. The exposure to thimerosal at a young age has a strong
correlation with health issues and with autism development. The Southwestern Medical
Center in Texas discovered epidemiological evidence that there was an association
between thimerosal containing vaccines and autism spectrum disorder(David A Geier.
2013). Monosodium Glutamate is a well known neurotoxin that has the power to cross
the placenta into a growing fetus. Research concludes that the ingredients in vaccines are
not safe and can have cataclysmic effects on the body.
A combination vaccine for pertussis, diphtheria, and tetanus is undoubtedly the most
dangerous of vaccines because of its onslaught on the immune system and has the
capability to leave susceptible children with neurological syndromes. This vaccine is
administered to mainly infants that have not yet developed a strong immune defense,
making the adverse effects much worse.
There have been many proposed causes of autism such as: inflammation, genetics,
and toxin exposure. Inflammation is associated with oxidative stress from free radical
damage. Genetic mutations impair metabolic pathways increasing oxidative stress. Toxins
create free radicals that steal electrons from healthy cells within the body resulting in
oxidative stress. Autism appears to be directly caused by oxidative stress within
susceptible tissues of the body, specifically the brain. Because all parts of a vaccine create
free radicals they undeniably have the potential to cause children to develope autism.
Oxidative damage is an imbalance between free radicals and the body’s ability to
neutralize those free radicals with electrons from antioxidants. Every disease and illness
involves oxidative stress. Those with inadequate antioxidant intake cannot properly
support their body during times of illness. Since vaccines cause oxidative stress the same
principle applies. The Menssana Research Inc. found that "the flu vaccination in healthy
humans elicited a prompt and sustained increase in breath bio-markers of oxidative
stress” (Phillips M1., 2010). This is after the administration of just one vaccination in an
adult. Imagine the oxidative stress in a child after the administration of six vaccinations
or more. The damage to the body will be unavoidable and the development of autism
Andrew Wakefield is a well-known gastroenterologist and researcher. He is famous
for proposing a link between the MMR vaccine and autism. “Onset of behavioral
symptoms was associated, by the parents, with measles, mumps, and rubella vaccination
in eight of the 12 children, with measles infection in one child, and otitis media in another.
All 12 children had intestinal abnormalities, ranging from lymphoid nodular hyperplasia
to aphthoid ulceration”(Wakefield A., 1998). Although his research clearly shows this
proposed link was the idea of the parents, Andrew Wakefield's work was discredited and
used as a weapon by pro-vaccinators. A study that could cause an unfavorable reaction
towards vaccines could pose a risk to the multibillion dollar industry. In fact, the
pharmaceutical companies that produce vaccinations cannot be liable for vaccine injuries
or reactions, instead there is a vaccine injury compensation program. Billions of dollars
have been awarded to those that have taken on the difficult process of getting
compensated. In England, where Andrew Wakefield’s work was done there is still no
compensation plan for vaccine injured individuals.
Brandon Guppy was born in 1992 a beautiful healthy baby with an apgar score of 9.
Brandon was administered all of the recommended vaccinations on time and with those
vaccinations came rashes, eczema, and thrush. Brandon then developed diarrhea and his
speech ended. Michelle, Brandon’s mother has devoted her life to raising awareness about
autism and how dangerous vaccines are. She knows that her son’s autism and daily
seizures are a result of vaccinations. Michelle shares on social media traumatic moments
that she encounters when her son experiences a devastating grand mal seizure, in hopes it
will raise awareness. There is a law preventing the pharmaceutical companies from being
held responsible for the pain and suffering that Brandon and his family experience every
day. And yet, still these companies claim that there is no correlation between autism and
the administration of vaccines. What about the thousands of parents claiming that there is?
Do their tragic experiences hold no merit? I hope that stories like Brandon’s and
Michelle’s will encourage parents to do their own research. People like Michelle are
inspiring change, because all decisions become our destiny.
Dr. Thomas Levy, a board certified cardiologist that has vast knowledge on oxidative
stress and disease shared his thoughts on the correlation between autism and vaccines. “I
believe that greater than 90% of autism and nonspecific neurobehavioral problems
in kids (attention deficit, hyperactivity, etc.) are directly due to the toxic hit of vaccines,
later to be worsened by all the other toxic hits babies and kids face in environment and
diet these days” (Levy T. MD., JD., 2016). Dr. Levy has exceptional knowledge on the
connection between oxidative stress and it being the root of all disease. Vaccines and the
viruses within them induce free radical damage and an onslaught of the human body. His
staggering 90% estimate would explain the dramatic increase in autism rates.
There is much fear mongering taking place in regard to vaccinations. Those that are
afraid to vaccinate their children because of information or intuition are not only being
shamed by the media but they are also being shamed by their healthcare providers.
Doctors are not experts on vaccines, as a matter of fact many doctors will confess they
have very little knowledge on vaccines. Yet, they are told to encourage the administration
of vaccines and vouch for their safety. Dr. Kalokerinos concluded after over forty years
as a doctor and working with vaccines, “They want to make it appear as if they are saving
these kids, but in actual fact they don’t. I am talking of those at the very top. Beneath that
level is another level of doctors and health workers, like myself, who don’t really
understand what they are doing. But I cannot see any other possible explanation: It is
murder and it is genocide” (Kalokerinos A., 1995).
Eight years ago I gave birth to my first child. Like many parents I vaccinated her
because I did not want her to die from mumps or get sick with chicken pox. Whether I
was going to vaccinate or not was never a topic of conversation. It was always just the
way things were supposed to happen. When the sparkle in my baby girls eye started to
fade I knew something was amiss in her little body and I had to wonder what I was doing
wrong. She developed the sort of anxiety you see in horror movies, that depict the main
character constantly running for her life. Could something so normal, something that was
meant to protect my daughter actually be causing harm? And if vaccines are so harmful
where are all the damaged children to prove it? It turns out they are not so hard to find.
You can find neighbors, coworkers, classmates, and even relatives that have experienced
adverse reactions to vaccines. I stopped vaccinating my children and I was terrified of
preventable diseases. It turns out those preventable diseases were not as scary as I
expected, especially in healthy children. Like the Association of American Physicians and
Surgeons said "Measles, mumps, rubella, hepatitis B, and the whole panoply of childhood
diseases are a far less serious threat than having a large fraction (say 10%) of a generation
afflicted with learning disability and/or uncontrollable aggressive behavior because of an
impassioned crusade for universal vaccination” (Orient J., MD., 1999). As a mother of 4
children I am courageously prepared to take on any disease, but I am not prepared to
welcome anymore preventable behavioral and physical disabilities into our lives.
The administration of vaccines should come with adequate knowledge. Parents
should be informed of ingredients and the side effects that are directly listed on the
vaccine inserts. Anyone is welcome to ask for them. Doctors that administer vaccines
should be educated on them and encourage a parent’s right to choose.
Autism is a devastating disorder that can and has altered the lives of many. It is a
direct result of oxidative damage within the body and because the makeup of vaccines are
toxic they result in oxidative damage. This evidence compels the conclusion that vaccines
can and will result in autism spectrum disorder. Are you willing to take that risk?
Christensen D., Et al., (2016) Prevalence and Characteristics of Autism Spectrum
Disorder Among Children Aged 8 Years — Autism and Developmental Disabilities
Monitoring Network, 11 Sites, United States, 2012. Atlanta, GA: CDC.
David A Geier, et al., (2013) A two-phase study evaluating the relationship between
Thimerosal-containing vaccine administration and the risk for an autism spectrum
disorder diagnosis in the United States. University of Texas Southwestern Medical
Center at Dallas, Dallas, TX: Pubmed.
Guppy M., (2016) Personal correspondence through messages.
Guppy M., (2016). My Journey Through Life with Autism, Seizures -and a Side of Crazy,
Mad, Wonderful. Retrieved from www.michellemguppy.blogspot.com/
Grabenstein JD., (2013) ImmunoFacts: Vaccines and Immunologic Drugs. St Louis, MO:
Wolters Kluwer Health.
Higging C., (1920). Horrors of Vaccination Exposed and Illustrated. Brooklyn, N. Y.
Kalokerinos A. MD., (1995). An Interview with Dr. Archie Kalokerinos MD. Interview
through International Vaccine Newsletter.
Levy T. MD., JD., (2016). Personal Correspondence through email.
Orient J., MD., (1999). Statement of the Association of American Physicians & Surgeons.
Tucson, AZ. Retrieved from http://whale.to/vaccines/statement....
Phillips M1, et al., (2010). Effect of influenza vaccination on oxidative stress products in
breath.Menssana Research Inc., Fort Lee, NJ: Pubmed.
Shaw CA., (2013). Aluminum in the central nervous system (CNS): toxicity in humans
and animals, vaccine adjuvants, and autoimmunity. Department of Ophthalmology
and Visual Sciences, University of British Columbia. Vancouver, BC, Canada:
Wakefield AJ., (1998). Ileal-lymphoid-nodular hyperplasia, non-specific colitis, and
pervasive developmental disorder in children. Retrieved from
Yuan C., et al., (2012). Aluminum overload increases oxidative stress in four functional
brain areas of neonatal rats. School of Medicine at Fu-Jen Catholic University. New
Taipei City, Taiwan: Pubmed.